The COVID pandemic has had many dire consequences, among them, revealing in crude and explicit ways the dramatic conditions of inequality and ordinary violence experienced by those othered in society because of race, gender and class. Catalyzed through the anti-racist demand of the BLM movement, there has been a raising awareness and claim to decolonize the university, sparkling acute debates related to the recognition of difference, broadening the representation of the students and staff populations to promote more inclusive learning environments, while also advocating for the recognition and validation of plural forms of knowledge. These questions connect to core aims of interdisciplinarity. In this brief presentation I want to explore the call to decolonize the university as a provocation to interdisciplinary studies and how it can foster alternative dialogues about teaching and research methodologies. Current global challenges, like the pandemic and the environmental destruction, reveal without doubt that the time of the mono-disciplinary scientific university is clearly reaching its end. Its colonial foundation is part of the problem, hence in this talk I intend to explore how decolonization matters for the future necessity for interdisciplinary teaching and research.